The toxicology of Isopropanol

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qiuranxuan
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Joined: Tue Jul 12, 2011 3:13 pm

The toxicology of Isopropanol

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Isopropyl is a common name for a chemical compound with the molecular formula C3H8O, Isopropa Isopropanol l is one of the most widely used solvents in the world.
Isopropyl alcohol and its metabolite, acetone, act as central nervous system (CNS) depressants. Around 15 g of isopropyl alcohol can have a toxic effect on a 70 kg human if left untreated. However, it is not nearly as toxic as methanol or ethylene glycol. Isopropyl alcohol does not cause an anion gap acidosis (in which as lowered blood serum pH causes depletion of bicarbonate anion) unlike ethanol and methanol. Isopropyl alcohol does however, produce an osmolal gap between the calculated and measured osmolalities of serum, as do the other alcohols. Overdoses may cause a fruity odor on the breath as a result of its metabolism to acetone, which is further metabolized to produce the nutrients acetate and glucose.
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