The Clinical Implications of Inositol

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hanlin
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The Clinical Implications of Inositol

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D-chiro-inositol (DCI) has been found in two double-blind studies to be an effective treatment for many of the clinical hallmarks of polycystic ovary syndrome (PCOS), including insulin resistance, hyperandrogenism, and oligo-amenorrhea. The impetuses for these studies were the observed defects in DCI metabolism in PCOS and the implication of DCI in insulin signal transduction.
Animal studies suggest inositol reduces the severity of the osmotic demyelination syndrome if given prior to rapid correction of chronic hyponatraemia. Further study is required prior to its application in humans for this indication.
Studies from in vitro experiments, animal studies, and limited clinical experiences, claim that inositol may be used effectively against some types of cancer, in particular, when used in combination with phytic acid.
Inositol has been used as an adulterant (or cutting agent) in many illegal drugs, such as cocaine, methamphetamine, and sometimes heroin. It is presumed that this use is connected with the substance's solubility and near-lack of taste (which is easily hidden by that of the drugs themselves).
Myo-inositol is naturally present in a variety of foods, although tables of this do not always distinguish between the bioavailable lecithin form, and the non-available phytate form in grains.According to research, foods containing the highest concentrations of myo-inositol (including its compounds) include fruits, beans, grains and nuts. Beans and grains, however, as seeds contain large amounts of inositol as phytate.
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